LAE1 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G11949 (LAE1) on chromosome 2 of Fusarium graminearum PH-1 encodes a protein containing a SAM-dependent methyltransferase superfamily domain with methyltransferase activity. The gene is associated with regulation of secondary metabolism, activation of gliotoxin anabolism, terrequinone A anabolism, sterigmatocystin anabolism, disruption of host phagocytosis, spore formation, DNA-dependent transcription, and methylation, and its product localises to the nucleus. Studies of related genes in other species connect the family to methyltransferase activity.