LIP1 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G12995 (LIP1) in Fusarium graminearum PH-1 on chromosome 2 encodes a secreted lipase belonging to the Lipase_secreted and AB_hydrolase domain families. The gene product has been annotated with lipase activity and triacylglycerol (TAG) lipase activity. LIP1 is associated with sexual reproduction, lipolysis, filamentous growth in response to starvation and biotic stimulus, and cellular response to starvation. The protein is localized to the extracellular space. The gene is also linked to the TRI8 protein (associated with T-2 toxin) and the LIP2 protein (associated with IL-17), as well as several other lipase-related genes (LIP4, LIP6, LIP7, LIP8, LIP9). Related genes in other species link the family to triacylglycerol lipase activity (EC 3.1.1.3).