TRI5 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G13111 (TRI5) on chromosome 2 of Fusarium graminearum PH-1 encodes trichodiene synthase, a member of the trichodiene synthase and isoprenoid synthase domain superfamily, with trichodiene synthase activity. This gene is associated with sesquiterpenoid anabolism, phytoalexin biosynthesis, defense response, innate immunity, and metabolic burst. It has also been connected to perithecium formation, asexual reproduction, pigmentation, seed germination, and the GABA shunt, polyamine metabolism and transport, carbon catabolite repression, mycose and fumonisin biosynthesis, and the shikimate pathway. Associations with traits include mycotoxin content, glucose content, phosphate content, and germination rate. Studies of related genes in other species link the family to trichodiene synthase activity (EC 4.2.3.6) and to reduced or unaffected pathogenicity in hosts such as wheat, oat, rye, maize, and soybean, particularly in the context of fusarium head blight, ear blight, and crown rot.