CP1 — Fusarium graminearum PH-1

Summary

FgCP1 (FGRAMPH1_01G13667) on chromosome 2 of Fusarium graminearum PH-1 encodes a serine carboxypeptidase belonging to the peptidase S10 family, with serine carboxypeptidase activity. The gene is associated with proteolysis, secondary metabolism, sexual reproduction, vacuolar protein sorting, Golgi-to-vacuole transport, zymogen activation, phytochelatin anabolism, cellular response to nitrogen starvation, and methylation. The product localizes to the fungal-type vacuole lumen, fungal-type vacuole, and extracellular. Phenotypic associations include abnormal nuclear fusion during mating, increased necrotic cell death, altered autophagy, decreased mitophagy and pexophagy, abnormal protein secretion, increased aneuploidy, and increased acquired thermotolerance.