ARF — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G13851 (ARF) on chromosome 2 of Fusarium graminearum PH-1 encodes a small GTPase of the ARF/SAR family, with GTP binding and GTPase activity, and is annotated as a G protein and protein membrane adaptor. The gene is associated with vesicle organization, ER-to-Golgi transport, intracellular protein transport, and positive regulation of protein exit from the ER. It is also linked to nuclear envelope and mitochondrial membrane organization, mitochondrial fission, cell growth mode switching from monopolar to bipolar, regulation of mitotic cytokinesis, positive regulation of mitotic entry, cellular response to AOS, and innate immunity. Localization evidence connects the product to the Golgi membrane, ER exit site, COPII vesicle coat, division septum, cell cortex, and mitochondria-associated membrane. Related genes in other species link the family to small GTPase-mediated vesicular trafficking.