SWI6 — Fusarium graminearum PH-1

Summary

FgSWI6 (FGRAMPH1_01G14767) on chromosome 2 of Fusarium graminearum PH-1 encodes a protein with an ankyrin repeats, characteristic of the SWI6-like transcription factor family. The product is annotated with promoter-specific chromatin binding, DNA-binding transcription repressor and activator activities for RNA polymerase II, and transcription coactivator activity. FgSWI6 is associated with the SBF and MBF complexes, localizes to chromatin, cytoplasm, cytosol, and nucleus, and is linked to diverse biological processes including sexual reproduction, sporulation, conidia formation, pigmentation, melanin biosynthesis, cell morphogenesis, cytokinesis, nuclear division, meiotic cell cycle modulation, antiviral and defense responses, steroid metabolism, and rRNA transcription. Studies of related genes in other species link the family to reduced virulence and associations with fusarium head blight and rice blast.