DCL2 — Fusarium graminearum PH-1

Summary

FgDCL2 (FGRAMPH1_01G15217) on chromosome 2 of Fusarium graminearum PH-1 encodes a protein with ribonuclease III and helicase activities, containing Dicer dimerisation, RNase III, dsRBD, DEAD/DEAH-box helicase, and ATP-binding domains. It is associated with siRNA processing, RNA-dependent gene silencing, regulation of antiviral response, antiviral response, conidia formation, autophagy, and homeostasis. The protein localises to both the cytoplasm and nucleus. Related genes in other species link the DCL2 family to reduced virulence.