PMG — Fusarium graminearum PH-1

Summary

FgPMG (FGRAMPH1_01G15765) on chromosome 2 of Fusarium graminearum PH-1 encodes an amino acid permease of the APC/YAT family, with L-arginine and L-lysine transmembrane transporter activity. The gene is associated with polyamine metabolism and transport, regulation of nitrogen utilization, filamentous growth, and amino acid import. The protein localizes to the plasma membrane, cell tip, Golgi, vacuole, and division site. Phenotypic associations include increased nutrient uptake and carbon utilization, increased fermentative growth, decreased nitrogen utilization, abnormal colony shape, altered cell cycle progression, and increased freeze-thaw and ionic stress resistance, alongside absent adhesion and hydrostatic pressure resistance. Studies of related genes in other species link the family to calcium sensitivity, acid sensitivity, and oxidative stress response.