ABCA — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G15627 (symbol ABCA, also known as ZRA1) on chromosome 2 of Fusarium graminearum PH-1 encodes an ABC transporter, possessing ATP hydrolase activity and ATP binding. This gene is associated with zearalenone biosynthetic process, toxin anabolism, xenobiotic detoxification by transmembrane export across the plasma membrane, response to toxic substance, and hypersensitivity. It is linked to extracellular transport, seed germination, DNA repair, and detoxification. The product localizes to the vacuolar membrane, plasmalemma, and membrane. Phenotypic associations include abnormal small molecule transport, increased sporulation rate, decreased cell death rate, delayed exit from G0, abnormal chronological and replicative lifespan, and altered nutrient uptake. Studies of related genes in other species link the family to plant height, leaf number, root length, drought tolerance, and reduced virulence.