PMG — Fusarium graminearum PH-1

Summary

FgPMG (FGRAMPH1_01G14133) on chromosome 2 of Fusarium graminearum PH-1 encodes a member of the amino acid permease family, possessing L-arginine and L-lysine transporter activity. The gene is associated with polyamine metabolism and transport, L-arginine and L-lysine import, regulation of nitrogen utilization, amino acid membrane transport, excretion, and filamentous growth. The encoded protein localizes to the plasma membrane, cell tip, fungal-type cell wall, Golgi membrane, and cell division site. Phenotypic associations link FgPMG to increased nutrient uptake and carbon source utilization, increased fermentative growth, decreased nitrogen source utilization, altered colony shape, decreased radiation resistance, increased freeze-thaw and ionic stress resistance, and abnormal prion state, chromosome segregation, and meiotic recombination. Related genes in other species are linked to sulfur utilization and calcium sensitivity.