MT1 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G14109 (MT1) on chromosome 2 of Fusarium graminearum PH-1 encodes a protein with a Sphingo_C9-MT domain and a SAM-dependent methyltransferase superfamily fold, and is annotated with methyltransferase activity. The gene is associated with glucosylceramide anabolism, sphingolipid metabolism, methylation, and filamentous growth. Its product localises to the plasma membrane, membrane, and extracellular vesicles. Related genes in other species link the family to sphingolipid C(9)-methyltransferase activity (EC 2.1.1.317) and to both unaffected pathogenicity and reduced virulence, as well as to associations with Fusarium head blight and hosts such as wheat, maize, and tomato.