ABC2 — Fusarium graminearum PH-1

Summary

FgABC2 (FGRAMPH1_01G12603) on chromosome 2 of Fusarium graminearum PH-1 encodes an ABC-type oligopeptide transporter with ATP hydrolase activity, belonging to the type 1 exporter family and containing ABC transporter-like ATP-binding and transmembrane domains. The gene is associated with oligopeptide export from the mitochondrion, sterol anabolism, secretion, membrane transport, and homeostasis, and its product localises to the mitochondrial inner membrane, plasma membrane, and general membrane. Phenotypic associations link FgABC2 to altered oxidative and osmotic stress resistance, abnormal cell cycle progression, decreased endocytosis, increased pexophagy, and changes in vacuolar morphology, protein/peptide accumulation, and colony colour. The gene is also connected to the related genes TLC1, NFT1, and MDL1. Studies of related genes in other species link it to leaf width and shape traits, salt tolerance, and oxidative stress response.