LIP1 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G12301 (LIP1) on chromosome 2 of Fusarium graminearum PH-1 encodes a carboxylesterase belonging to the carboxylesterase B and alpha/beta hydrolase families, with carboxylesterase and triacylglycerol lipase activity. The gene is associated with (M)-viriditoxin anabolism, lipolysis, and lipid metabolism, and its product is localised extracellularly. LIP1 is also linked to the related gene LIP3. Studies of related genes in other species connect the family to carboxylic ester hydrolase activity (EC 3.1.1.1 and 3.1.1.3) and to unaffected pathogenicity, though these associations are not established for LIP1 itself.