MAT1-1-3 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G11097 (MAT1-1-3) on chromosome 2 of Fusarium graminearum PH-1 encodes a protein containing an SRY-related HMG-box transcription factor-like domain and an HMG box domain. The product has sequence-specific DNA binding, bending, and transcription activator activity, with RNA polymerase II cis-regulatory region binding and bending activities, and transcription coactivator activity. It localises to the nucleus, chromatin, the spindle pole body, and the RNA polymerase II transcription regulator complex. The gene is associated with mating type determination, perithecium formation, single fertilisation, sexual reproduction, and positive regulation of the meiotic cell cycle. It is also linked to filamentous growth in response to starvation and biotic stimulus, cellular response to starvation, and negative regulation of transcription by RNA polymerase II. Studies of related genes in other species connect the family to unaffected pathogenicity and fusarium ear blight.