TAD2 — Fusarium graminearum PH-1

Summary

FgTAD2 (FGRAMPH1_01G11273) on chromosome 2 of Fusarium graminearum PH-1 encodes a protein with a cytidine deaminase-like domain and CMP/dCMP domain, possessing tRNA(Ala)-A34 deaminase activity, zinc and ATP binding. The gene is associated with tRNA wobble adenosine-to-inosine editing, translation initiation, and sexual reproduction. Its product localises to the cytoplasm, nucleus, and tRNA-A34 deaminase complex. Related genes in other species link the family to tRNA-specific adenosine deaminase activity (EC 3.5.4.33).