SC — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G11061 (SC, MET3) on chromosome 2 of Fusarium graminearum PH-1 encodes a bifunctional enzyme with ATP:sulfate adenylyltransferase and adenylylsulfate kinase activities, placing it in the sulfate adenylyltransferase/APS kinase family. The gene is associated with cysteine and hydrogen sulfide anabolism, pigment anabolism, protein synthesis, and sexual reproduction, and its product localises to the cytoplasm. Associations with numerous phenotypes have been recorded, including increased vegetative growth rate, increased hyperosmotic stress resistance, increased respiratory metabolism, decreased cold sensitivity, altered cell cycle progression, abnormal endomembrane system morphology, and effects on autophagy, pexophagy, prion inheritance, and pseudohyphal growth. Studies of related genes in other species link the family to sulfate assimilation and methionine biosynthesis.