ABCA — Fusarium graminearum PH-1

Summary

FgABCA (FGRAMPH1_01G09623) on chromosome 2 of Fusarium graminearum PH-1 encodes an ABC transporter of the PDR/CDR subfamily, possessing ATP-coupled transmembrane transporter activity and ATP hydrolase activity. The protein localises to the plasma membrane and is associated with xenobiotic detoxification via transmembrane export, response to antibiotics, toxin anabolism, and DNA repair. It has been linked to extracellular transport, seed germination, and hypersensitivity. Phenotypic associations include abnormal small molecule transport, increased sporulation rate, decreased cell death rate, altered vacuolar distribution and transport, delayed mitophagy, abnormal pseudohyphal growth, and altered nutrient uptake.