RDP1 — Fusarium graminearum PH-1

Summary

FgRDP1 (FGRAMPH1_01G10647) on chromosome 2 of Fusarium graminearum PH-1 encodes an RNA-dependent RNA polymerase (RdRP) with an RDRP_core domain and eukaryotic-type RNA-dep_RNA_pol domain, possessing RdRP activity and RNA binding. This gene is associated with RNA interference pathways, including siRNA processing, RNAi-mediated co-transcriptional gene silencing, RNAi-like chromatin silencing, and RNAi-mediated heterochromatin assembly at centromeres. It is linked to sexual reproduction, ascus development, meiosis, chromosome division, morphogenesis, maintenance of G0 phase, and methylation. The encoded product localizes to the RNA-directed RNA polymerase complex (RDRC), subtelomeric and centric heterochromatin, mating-type region heterochromatin, chromatin, cytoplasm, cytosol, and nucleus. Related genes in other species link the family to RNA-dependent RNA polymerase activity (EC 2.7.7.48).