MYO1 — Fusarium graminearum PH-1

Summary

FgMYO1 (MYO1) on chromosome 2 of Fusarium graminearum PH-1 encodes a protein with domains including DUF7491, Myosin_S1_N, Myosin_N, Myosin_head_motor_dom, Kinesin_motor_dom_sf, and P-loop_NTPase, and has calcium-dependent ATPase, microfilament motor, calmodulin-binding, F-actin-binding, small GTPase-binding, hydrolase, ATP hydrolase, and ATP binding activities. It is associated with response to mycotoxin, endomembrane organization, protein localisation in actin fusion focus, actin filament bundle retrograde transport, vesicle transport along actin filament, Golgi division, formin-nucleated actin cable assembly, organelle inheritance, nuclear migration during mitotic telophase, actin filament bundle organization, actomyosin contractile ring assembly actin filament bundle convergence, peroxisome inheritance, ER inheritance, receptor-mediated endocytosis, intracellular mRNA localization, membrane addition at site of cytokinesis, and mitotic actomyosin contractile ring contraction. The gene is linked to phenotypes including absent or decreased septum formation, decreased cytokinesis rate, delayed chromosome segregation, absent cell fusion, arrested anaphase progression, abnormal mating and prion inheritance, and absent innate thermotolerance. It localizes to the myosin V complex, myosin filament, LINC complex, formin-nucleated actin cable, cortical cytoskeleton