SSO1 — Fusarium graminearum PH-1

Summary

FgSSO1 (FGRAMPH1_01G06855) on chromosome 1 of Fusarium graminearum PH-1 encodes a syntaxin-family SNARE protein containing Syntaxin_N and T_SNARE domains. The gene product is associated with SNARE binding, and is linked to vesicle fusion, exocytosis, endocytosis, intracellular protein transport, autophagy, and protein secretion. It localises to the prospore membrane leading edge, plasma membrane raft, endomembrane system, extracellular vesicles, endosomes, cell tips, and division sites. FgSSO1 is associated with ascospore formation, hyphal growth, morphogenesis, and FSM assembly. Phenotypic associations include abnormal endoplasmic reticulum and Golgi distribution, delayed sporulation and protein transport, increased necrotic cell death, and aberrant cell cycle progression. Related genes in other species link the family to reduced virulence.