BD (FGRAMPH1_01G07323) — Fusarium graminearum PH-1

Summary

FgBD (FGRAMPH1_01G07323) on chromosome 1 of Fusarium graminearum PH-1 encodes a small GTPase of the Ras-type family with GTP binding and GTPase activity, and is annotated for G protein activity. This gene is associated with Ras protein signal transduction, regulation of conidium formation, spore germination, sexual reproduction, hyphal growth, and establishment or maintenance of cell polarity, as well as nitrate metabolism and signal transduction. It localises to the plasmalemma. Phenotypic associations include decreased vacuolar transport and oxidative stress resistance, absent bipolar budding and prion inheritance, increased mating-type switching, and altered cell cycle progression, protein transport, and flocculation. Sequence similarity links the family to reduced virulence in other fungi and to traits such as protein content and oxidative stress response.