ATF1 — Fusarium graminearum PH-1

Summary

FgATF1 (FGRAMPH1_01G07385) on chromosome 1 of Fusarium graminearum PH-1 encodes a bZIP transcription factor with DNA-binding transcription activator activity specific to RNA polymerase II, along with nucleosome binding and recombination hotspot binding functions. The gene is associated with sexual and asexual reproduction, reciprocal meiotic recombination and its activation, suppression of meiotic recombination, penetration peg formation, defense response, response to nitrosative stress and hydrogen peroxide, nitrate assimilation, RNA surveillance and splicing, negative regulation of antisense RNA transcription and adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling, and upregulation of aflatoxin anabolism. The product localizes to the nucleus, chromatin, heterochromatin, and the Atf1-Pcr1 complex. Studies of related genes in other species link the family to virulence, oxidative stress response, and calcium and acid sensitivity.