nbr1 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G07025 (symbol nbr1) in Fusarium graminearum PH-1 on chromosome 1 encodes a ZZ-type zinc finger domain-containing protein with cargo receptor activity and zinc binding. The gene is associated with autophagy, receptor breakdown, stomatal closure, jasmonic acid signaling, 5-aminolevulinic acid metabolism, flavonoid anabolism, and secondary metabolism. Its product localises to multivesicular bodies, the fungal-type vacuole lumen, and the Golgi complex. Studies of related genes in other species link the family to cytoplasm-to-vacuole targeting via the NVT pathway and to the NVT complex. The gene is also connected to related sequences in other species.