PLD1 — Fusarium graminearum PH-1

Summary

FGRAMPH1_01G06831, designated FgPLD1, encodes a phospholipase D with phospholipase D activity and phosphatidylinositol-3-phosphate binding, containing PLipase_D_fam, PLD-like_dom, and PX_dom domains. In Fusarium graminearum PH-1, this gene is associated with perithecium formation, asexual reproduction, hyphal growth, spore formation, meiotic cell cycle, homologous recombination, phospholipid breakdown, phosphatidic acid anabolism, and phosphoinositide-mediated signaling. The product localizes to the cytosol. Phenotypic associations include abnormal filamentous growth, absent spore germination, increased mating efficiency, sterile phenotype, decreased cell fusion, abnormal spore wall formation, and decreased meiosis. Studies of related genes in other species link the family to reduced virulence.