PSD2 — Candida albicans

Summary

C5_04680W_A (PSD2) in Candida albicans encodes a protein with a PSD type 2 domain, a C2 domain, and is associated with phosphatidylserine decarboxylase activity (EC 4.1.1.65), L-tryptophan decarboxylase activity, phospholipid binding, and metal binding. The protein is localized to multiple membranes including the Golgi, endoplasmic reticulum, mitochondrial inner membrane, endosome, vacuole, and nuclear envelope. PSD2 is associated with phosphatidylserine, phosphatidylethanolamine, and phosphatidylcholine anabolism, the Kennedy pathway, protein autoprocessing, psilocybin biosynthetic process, adiposome formation, filamentous growth in response to chemical, starvation, and biotic stimuli, secretion, and lipid metabolism. Phenotypic associations include decreased colony size, abnormal pseudohyphal growth, increased rate of fermentative metabolism, decreased oxidative phosphorylation, increased rate of apoptosis, cell cycle arrest, abnormal cytokinesis, and decreased rate of nutrient uptake and mitochondrial transport.