MID1 — Candida albicans

Summary

C5_03990W_A (MID1, CaMID1) on Candida albicans chromosome 5 encodes a member of the Mid1/Ehs1 protein family with calcium channel activity and protein phosphatase regulator activity. The gene is associated with calcium import into cells, calcium signaling, and localization to the plasma membrane as part of a voltage-gated calcium channel complex. MID1 is associated with hyphal growth, biofilm formation, invasive growth, morphogenesis, cytokinesis, mitosis, thigmotropism, cellular mechanical stimulus response, response to stress, fungal-type cell wall organization, ergosterol anabolism, phytochrome chromophore anabolism, and bioluminescence. Phenotypic associations include abnormal cell fusion, mating, shmoo formation, budding, flocculation, adhesion, colony shape, plasma membrane morphology, and altered endocytosis, apoptosis, necrotic cell death, and recovery from pheromone-induced cell cycle arrest. The gene is also associated with calcium sensitivity and oxidative stress response.