CAT1 — Candida albicans

Summary

C5_02790C_A (CAT1, also known as GAP1) in Candida albicans encodes an amino acid permease with L-arginine and L-lysine transporter activity, belonging to the amino acid permease family. This gene is associated with amino acid import, nitrogen catabolite repression, nitrogen utilization, germ tube formation, cell-cell signaling, regulation of growth and response to stress, as well as responses to glutathione, iron, and oxidative stress. It is linked to phenotypes including altered nutrient uptake, decreased adhesion, abnormal plasma membrane morphology, delayed sporulation, decreased endocytosis, and increased necrotic cell death. The encoded protein localizes to the plasma membrane, cell tip, Golgi membrane, extracellular vesicles, and fungal-type cell wall. Related genes in other species connect the family to phosphate content.