PST1 — Candida albicans

Summary

C5_02460C_A (PST1, also known as ECM331) in Candida albicans encodes a protein belonging to the CWI-Assembly_Regulator family and the Rcpt_L-dom_sf superfamily. The gene is associated with ascospore wall biogenesis, cell wall organization, plasma membrane organization, biofilm formation, protein secretion, TOR signaling, stress response, immune response, phagocytosis, chitin anabolism, sterol metabolism, and regulation of DNA replication. It localizes to the ascospore wall, fungal-type cell wall, external side of the plasma membrane, and cytoplasm. Phenotypic associations include abnormal budding, cytokinesis, cell cycle progression, increased flocculation and chitin deposition, decreased mating efficiency and acquired thermotolerance, altered redox state, and increased sporulation efficiency. Studies of related genes in other species link the family to biomass yield and phosphate content.