ZRFC — Candida albicans

Summary

C4_06970C_A (ZRFC, ZRT1) in Candida albicans chromosome 4 encodes a ZIP family protein with high-affinity zinc transmembrane transporter activity, zinc ion transmembrane transporter activity, and zinc binding. The gene is associated with zinc transport, zinc import, zinc ion membrane transport, and cellular zinc ion homeostasis. It has been connected to germ tube formation, biofilm formation, filamentous growth, morphogenesis, NK cell activation, cell activation, and tube formation. The product localizes to the ER membrane and plasmalemma. ZRFC is also linked to disseminated candidiasis in Mus musculus.