CP1 — Candida albicans

Summary

C5_01450W_A (CP1, also known as PRC2) on Candida albicans chromosome 5 encodes a serine carboxypeptidase with a Peptidase_S10 domain and AB_hydrolase fold, classified under EC 3.4.16.-. The gene is associated with phytochelatin anabolism, zymogen activation, cellular response to nitrogen starvation, digestion, proteolysis, and protein synthesis, and its product localizes to the fungal-type vacuole lumen and vacuole. Phenotypic associations include altered entry into G0, increased acquired thermotolerance, abnormal nuclear fusion during mating, increased aneuploidy, and changes in autophagy, cell death, and lifespan. Studies of related genes in other species link the family to apoplastic effector function and floral organ identity, though these are not established for C. albicans.