CCN1 — Candida albicans

Summary

CCN1 (C5_01680C_A) in Candida albicans encodes a cyclin CLN family protein with cyclin-box and cyclin-like domains, and is annotated with cyclin-dependent protein serine/threonine kinase activator activity and regulator activity. This gene is associated with regulation of the G1/S transition of the mitotic cell cycle, cell cycle G1/S phase transition, mitotic G1 cell size control checkpoint, upregulation of DNA replication and G1/S transition, regulation of cell morphogenesis, cell budding, negative regulation of ascospore formation and meiotic cell cycle, regulation of cell cycle switching from mitotic to meiotic, and gastrulation. The protein localizes to the CDK holoenzyme, microtubule organizing center, spindle pole bodies, meiotic and mitotic spindles, nucleoplasm, nuclear periphery, and telomeric chromosome regions. Studies of related genes in other species support the family's conserved role in cell cycle control.