CAT1 — Candida albicans

Summary

C5_01800C_A (CAT1, also known as HIP1, PER1, GAP1, TAT2, and ISP5) in Candida albicans encodes an amino acid permease with L-arginine and L-lysine transporter activity. This gene is associated with the regulation of growth, stress response, germ tube formation, circadian rhythm, nitrogen catabolite repression, and cell-cell signaling. It is linked to processes including amino acid import, phospholipid transport, the glyoxylate cycle, and response to glutathione and iron. Localization evidence links the product to the plasma membrane, cell tip, Golgi membrane, and fungal-type cell wall. Phenotypic associations include altered nutrient uptake, decreased adhesion, abnormal cell cycle progression, delayed sporulation, increased necrotic cell death, and absence of hydrostatic pressure resistance and fermentative growth. Related genes in other species connect the family to phosphate content.