CZF1 — Candida albicans

Summary

C4_06820C_A (CZF1) on Candida albicans chromosome 4 encodes a Zn2Cys6 DNA-binding domain transcription factor with RNA polymerase II-specific DNA-binding activity. The protein localises to the nucleus and is associated with the regulation of filamentous growth, germ tube formation, phenotypic switching, quorum sensing, single-species biofilm formation on inanimate substrates, flocculation, cell-substrate adhesion, and symbiotic interaction. It is also linked to the response to farnesol, intracellular transport, sulfur metabolism, glucan anabolism, and oxidative stress response.