CNH1 — Candida albicans

Summary

CNH1 (C4_00040W_A) in Candida albicans encodes a protein belonging to the cation/H⁺ antiporter family, with sodium transporter, potassium transporter, and metal ion transmembrane transporter activities. The gene is associated with cellular sodium and potassium ion homeostasis, salinity response, regulation of membrane potential, and cell pH reduction. It is linked to germ tube formation, biofilm formation, and wound healing, as well as to traits including sodium concentration, potassium content, and photosynthetic rate. Phenotypic associations connect CNH1 to hyperosmotic stress resistance, desiccation resistance, ionic stress resistance, cell death, and cell cycle progression through G2/M phase. The protein localises to the plasma membrane, particularly at cell tips, and to the perinuclear ER membrane and nuclear membrane-ER network.