BRG1 — Candida albicans

Summary

C1_05140W_A (BRG1) in Candida albicans chromosome 1 encodes a GATA-type zinc-finger protein with DNA-binding transcription activator activity, transcription cis-regulatory region binding, sequence-specific DNA binding, and zinc binding. The gene is associated with cell fate specification and determination, filament development, chlamydospore formation, sexual reproduction, positive regulation of sexual sporulation, membrane depolarization, nucleosome disassembly, upregulation of single-species biofilm formation on inanimate substrate, upregulation of filamentous growth of a population of unicellular organisms, disruption of host phagocytosis, response to heat, pheromone response, glycerol anabolism, chitin anabolism, sterol metabolism, TOR signaling, cell morphogenesis, and oxidative stress response. The product localizes to chromatin and the nucleus. Related genes in other species include BRG1 (mouse) and nsdD (Aspergillus nidulans).