PDCA — Aspergillus nidulans FGSC A4
Summary
The Aspergillus nidulans gene PDCA (ANIA_04888) on chromosome 3 encodes a pyruvate decarboxylase (pdcA), an enzyme with pyruvate decarboxylase activity (EC 4.1.1.1) that binds thiamine pyrophosphate and magnesium. It is associated with ethanol fermentation and the biological process GO:0000949. The encoded protein localises to the cytosol, nucleus, and fungal biofilm matrix, and is also linked to cell-bound compartments. Studies of related genes in other fungi connect the PDCA family to oxidative stress response.
Annotations
- Chromosome
- 3
- Related genes
- pdcA, PDCA
- GO terms
- Nucleus, Cytosol, Pyruvate Decarboxylase Activity, cell bound, Mg binding, TPP binding, GO:0000949, ethanol fermentation
- Publications
- PMID:41050196, PMID:39464399, PMID:9210590, PMID:19146970, PMID:15625313, PMID:30611835, PMID:8221939, PMID:7725793
- Traits
- oxidative stress response