NOSA — Aspergillus nidulans FGSC A4

Summary

ANIA_05170 (NOSA, also known as ADV-1 or ZC232) in Aspergillus nidulans FGSC A4 on chromosome 5 encodes a Zn(2)-C6 fungal-type domain-containing protein with DNA-binding transcription factor activity specific to RNA polymerase II. It is associated with fruiting body formation, mycotoxin and sterigmatocystin biosynthesis, secondary metabolism, protein secretion, proteolysis, homeostasis, and DNA-dependent transcription, and localises to the nucleus. The gene is linked to germination rate. Related genes in other species, such as RosA and Pro-1, are C6 transcription factors, though these associations are not yet established in A. nidulans.