METR — Aspergillus nidulans FGSC A4

Summary

ANIA_05218 (METR, AnMETR) on chromosome 5 encodes a bZIP transcription factor, annotated as a hypothetical second sulfur transcription regulator MetZ. It has RNA polymerase II transcription regulatory region sequence-specific DNA binding and DNA-binding transcription activator activity. The gene is associated with regulation of sulfur metabolism, sulfur amino acid and methionine metabolism, secondary metabolism including gliotoxin and penicillin anabolism, the GABA shunt, glyoxylate cycle, glycerol anabolism, fermentation, and signal transduction. It is linked to positive regulation of transcription by RNA polymerase II and localises to the nucleus. Related genes in other species link the bZIP family to sulfur metabolism regulation.