TRPB — Aspergillus nidulans FGSC A4

Summary

ANIA_05444 (symbol TRPB, preferred name AnTRPB) on chromosome 5 of Aspergillus nidulans FGSC A4 encodes a tryptophan synthase beta subunit, an enzyme with tryptophan synthase activity (EC 4.2.1.20) that catalyses tryptophan formation. The gene is associated with calcium signalling, hyphal growth, autophagy, and homeostasis, and its product localises to the cytoplasm and cytosol. Studies of related genes in other species link the TRPB family to tryptophan biosynthesis, though these associations are not yet established for this specific gene.