PHOB — Aspergillus nidulans FGSC A4

Summary

ANIA_05156 (PHOB, AnPHOB) on chromosome 5 of Aspergillus nidulans FGSC A4 encodes a cyclin PHO80-like protein with cyclin-dependent protein serine/threonine kinase regulator activity and protein kinase binding. This gene is associated with negative regulation of conidium formation, sporocarp development involved in sexual reproduction, downregulation of sister chromatid cohesion, intracellular Pi homeostasis, programmed cell death, response to nutrient, nuclear division, cell cycle control, conidia formation, signaling, biofilm formation, meiosis, morphogenesis, cell death, and DNA-dependent transcription. The product localizes to the CDK holoenzyme, mitotic spindle pole body, cell division site, cytosol, and nucleus. Related genes in other species link the family to cyclin-dependent protein kinase regulator Pho80 function.