gal4 — Aspergillus nidulans FGSC A4

Summary

ANIA_04972 (gal4) on chromosome 3 of Aspergillus nidulans FGSC A4 encodes a Zn(II)2Cys6 transcription factor with sequence-specific DNA binding activity, including RNA polymerase II cis-regulatory region binding. This gene is associated with upregulation of transcription from RNA polymerase II promoters by galactose, positive regulation of metabolism, and DNA-dependent transcription. It is also linked to nitrate assimilation and aflatoxin and sterigmatocystin anabolism. The encoded protein localises to the membrane, cytoplasm, and nucleus. Studies of related genes in other species connect this family to the regulation of secondary metabolism and carbon source utilisation.