CNXH — Aspergillus nidulans FGSC A4

Summary

ANIA_04841, symbol CNXH (also known as AnCNXH, MOCS2, or AnMOCS2) on chromosome 3 of Aspergillus nidulans FGSC A4, encodes a protein with molybdopterin synthase activity (EC 2.8.1.12), belonging to the MoaE superfamily and MOCS2B eukaryotic domain. This gene is associated with molybdopterin cofactor anabolism and molybdenum cofactor (Moco) biosynthesis, and its product localises to the MPT synthase complex and cytosol. It has been connected to molybdenum content. Studies of related genes in other species link the CNXH family to these same biosynthetic pathways, though such roles are not yet established for this specific gene.