aflJ — Aspergillus nidulans FGSC A4

Summary

ANIA_04833 (aflJ) on chromosome 3 of Aspergillus nidulans FGSC A4 encodes a GDXG lipolytic enzyme of the AB hydrolase superfamily with versiconal hemiacetal acetate esterase activity and carboxylic ester hydrolase activity, also annotated for FAD binding and redox activity. The gene is associated with aflatoxin anabolism, secondary metabolism, lipolysis, and morphogenesis, and its product localises to both the cytosol and nucleus. Studies of related genes in other species link the family to additional esterase/lipase functions and to Fusarium pathogens, though these associations are not established for A. nidulans itself.