MAT2 — Aspergillus nidulans FGSC A4

Summary

ANIA_04734 (MAT2, also known as MAT1-2 or AnMAT1-2) on chromosome 3 of Aspergillus nidulans FGSC A4 encodes a protein containing an SRY-related HMG-box transcription factor-like domain and an HMG box domain. The gene product is a sequence-specific DNA-binding transcription activator with RNA polymerase II cis-regulatory region binding and bending activities, and it also has transcription coactivator activity. MAT2 is associated with mating type determination, sexual and asexual reproduction, single fertilization, ascospore formation, positive regulation of the meiotic cell cycle, cell differentiation, filamentous growth in response to starvation, cellular response to starvation, osmotic response, secondary metabolism, and anaphase. It localizes to the nucleus, chromatin, the RNA polymerase II transcription regulator complex, and the spindle pole body.