SEC1 — Aspergillus nidulans FGSC A4

Summary

ANIA_04724 (SEC1, AnSEC1) encodes a member of the Sec1 family superfamily, characterized by Sec1-like domains, and is annotated with syntaxin and SNARE binding activities. In Aspergillus nidulans, this gene is associated with multiple vesicle fusion processes, including Golgi, vacuole, and ER-to-Golgi transport, as well as protein transport and intracellular transport. The encoded product localizes to Golgi, vacuolar, ER, and plasma membranes, endosomes, cell tips, and division sites. Phenotypic associations link SEC1 to delayed sporulation, meiosis, nuclear fusion, and vacuolar transport, abnormal Golgi and ER distribution, decreased cell fusion and endocytosis, and altered chitin deposition and spore wall formation.