WC-2 — Aspergillus nidulans FGSC A4

Summary

ANIA_03607 (WC-2, also known as lreB) on chromosome 2 of Aspergillus nidulans FGSC A4 encodes a transcription factor with a PAS domain and photoreceptor activity. It binds sequence-specific DNA and cis-regulatory regions, and is localized to both the cytoplasm and nucleus. The gene is associated with the regulation of DNA-templated transcription, rhythmic processes, spore germination, germ tube and hyphal growth, tube formation, morphogenesis, mating, secondary metabolism, pigment anabolism, and mycotoxin anabolism. It has also been linked to respiration rate. Studies of related genes in other species connect the family to red light sensitivity and reduced virulence.