BRLA — Aspergillus nidulans FGSC A4

Summary

ANIA_00973 (BRLA, brlA) on chromosome 8 of Aspergillus nidulans FGSC A4 encodes a C2H2-type zinc-finger transcription factor that binds DNA in a sequence-specific manner at cis-regulatory regions and acts as a transcriptional co-regulator. The gene is associated with the regulation of asexual sporulation, conidiophore development, and positive regulation of conidium formation, as well as sexual sporulation, cleistothecium formation, fruiting body formation, and karyogamy. It is linked to temporal regulation of development, developmental induction, spore dispersal, response to red light, mannitol anabolism, cell volume homeostasis, autolysis, and regulation of growth. The gene is also connected to the regulation of sterigmatocystin biosynthetic process, sporogenesis, germination rate, and oxidative stress response. Its product localises to the nucleus, chromatin, and transcription regulator complex.