RPL5 — Aspergillus nidulans FGSC A4

Summary

ANIA_01013, designated AnRPL5 on Aspergillus nidulans chromosome 8, encodes a large ribosomal subunit protein uL18 C-terminal eukaryotes domain-containing protein that binds 5S rRNA and is a structural constituent of the ribosome. The gene is associated with ribosomal large subunit assembly, translation, cytoplasmic translation, ribosome biogenesis, and rRNA processing, and localises to the cytosolic large ribosomal subunit, cytosol, and nucleus. AnRPL5 is associated with numerous phenotypes including delayed sporulation, meiosis, cytokinesis, and exit from G0 stationary phase, as well as decreased pheromone sensitivity, increased critical cell size at the G1 checkpoint, abnormal spore wall and septum formation, decreased chitin deposition, increased desiccation resistance, and altered prion inheritance and RNA modification. Related genes in other species are linked to protein content traits.