qutA — Aspergillus nidulans FGSC A4

Summary

ANIA_01134 (qutA) on chromosome 8 of Aspergillus nidulans FGSC A4 encodes a Zn2Cys6 DNA-binding domain transcription factor. The gene is associated with quinate breakdown, the shikimate pathway, and monocarboxylic acid metabolism, as well as with positive regulation of transcription by RNA polymerase II, signal transduction, and upregulation of filamentous growth in response to biotic stimulus. The encoded product is localised to the nucleus and membrane and has sequence-specific DNA binding and zinc ion binding activities. Studies of related genes in other species link the family to quinate catabolism regulation.