VE1 — Aspergillus nidulans FGSC A4

Summary

The Aspergillus nidulans gene VE1 (ANIA_01052) on chromosome 8 encodes a velvet domain-containing protein. The gene is associated with negative regulation of conidiophore development, positive regulation of asexual sporulation, perithecium development, fruiting body formation, and sexual sporulation. VE1 is linked to the anabolism of carotenoids and cephalosporin C, and the regulation of penicillin metabolism. The encoded protein localises to both the cytoplasm and nucleus and is associated with blue light response, cell volume homeostasis, and membrane docking. Related genes in other species are linked to reduced virulence.